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10/Apr/2024

On Wednesday 3rd April, Dr+Vet was honoured to welcome leading veterinary ophthalmologist Maria Simó for our first webinar on Keratoconjunctivitis Seca (KCS) in dogs. During this virtual event, María Simó shared her knowledge and experience in the diagnosis and treatment of this common but often underestimated eye disease. Today, we can finally announce that the full video, with subtitles in English (and other languages automatically), is available for viewing on our blog and our YouTube channel! Attached to this article, you will find the direct link to the video so you can access it and deepen the knowledge shared by María Simó.

About Maria Simó:

Maria Simó is a renowned veterinary ophthalmologist with a solid background and extensive experience in the field of veterinary ophthalmology. Graduated in Veterinary Medicine from the Autonomous University of Barcelona, María has completed several postgraduate courses and works as an ophthalmologist at the prestigious Instituto Veterinario Oftalmológico (IVO) in Barcelona.

Contenido del Webinar:

Maria Simó talked us through the basics of Keratoconjunctivitis Seca, from diagnostic methods to the most effective treatment options, exploring in detail how to approach this disease in a comprehensive way.

One of the main conclusions of the webinar was the importance of not relying solely on the Schirmer test to diagnose KCS. María Simó emphasised the need for a complete and detailed assessment, as well as the use of additional diagnostic tools for a correct diagnosis, as without all the information, ineffective treatments may be prescribed. She also talked about the importance of referring cases that do not resolve correctly in order to fully evaluate them.

 

We thank all participants for their support.

The webinar on Keratoconjunctivitis Seca with Maria Simó was a great success, and we would like to thank everyone who joined us for this educational event. We hope that this resource will be a valuable source of information for all veterinarians interested in veterinary ophthalmology. Feel free to check out the full video and share it with your colleagues.

Stay tuned to our social media and website for more information on future of Dr+Vet events and educational resources!


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25/Mar/2024

Keratoconjunctivitis Sicca (KCS), also known as “dry eye,” is a common ophthalmic condition in dogs and cats that affects the ocular surface, specifically the cornea and conjunctiva.

This disease results from the deficiency of some of the phases of the tear film, which leads to tear hyperosmolarity and, consequently, a series of ocular complications that can compromise the visual health of the animal.

The structure of the tear

To better understand KCS, it is important to know the three layers that make up the tear film and their functions:

  • Mucinous layer: This layer, the innermost, modifies the surface tension of the tear so that it adheres and distributes properly over the surface of the eye. Mucin is produced and secreted mainly in conjunctival goblet cells.
  • Aqueous layer: The intermediate layer, and the most abundant, hydrates the ocular surface and transports nutrients and oxygen essential for the metabolism of the cornea. It also acts as a flushing mechanism to remove debris and foreign bodies. This watery portion is produced and secreted in the main and accessory lacrimal glands.
  • Lipid layer: The outermost layer protects the aqueous layer from evaporation, allowing the tear to remain in the eye longer. In addition, it increases the surface tension of the tear, preventing overflow over the edge of the eyelid and lubricating the eyelids. This layer is produced and secreted mainly in the meibomian glands.

KCS classification

The KCS can be classified into two main types:

  • Qualitative KCS: It is produced by a pathological decrease in the lipid or mucoid components of the tear film, which makes it difficult for it to remain on the cornea, either due to excess evaporation or difficulty adhering. It is usually due to damage or inflammation in the meibomian glands or goblet cells of the conjunctiva.
  • Quantitative KCS: It is produced by a pathological decrease in the aqueous component of the tear film. It can have various causes, the most common being localized and chronic immune-mediated inflammation of the lacrimal gland. This is the most common form of KCS, and in most cases it progresses to a mixed form (quantitative and qualitative) over time.

What symptoms does it cause?

Symptoms of KCS may include mucosal exudate, conjunctival hyperemia, corneal opacity, neovascularization, corneal edema, and ulceration, among others. The diagnosis of KCS requires a thorough evaluation of the patient’s medical history and specific ophthalmological tests, such as the Schirmer Test, Fluorescein Test, and the Lysamine Green Test.

What treatment is used?

Treatment of KCS may include artificial tears, topical immunosuppressants, and surgical treatments, depending on the severity and underlying cause of the disease. Additionally, supplementation with specific nutraceuticals such as LACRIMALIS+ can help manage this disease, offering natural help to maintain pets’ eye health.

 

If your pet presents symptoms compatible with this disease, go to your trusted veterinarian for correct diagnosis and treatment.


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04/Mar/2024

This event brings together thousands of professionals from the sector each year.

For the second consecutive year, Dr+Vet sponsors the Iberzoo-Propet AMVAC 2024 congress, the largest event on products and services related to pets, which will take place in Madrid from March 13 to 15.

During these days we will have the opportunity to connect with professionals from across the veterinary sector and share our latest innovations in veterinary nutraceuticals.

During this congress we will present a novelty in our ophthalmological range: RetinaeXL. The Retinae product has been part of the Dr+Vet catalog since its inception and now receives a new presentation adapted to larger breeds that suffer from hereditary idiopathic retinal degeneration.

Retinae XL: retina protection for XL dogs

The novelty of this congress is RetinaeXL. This product maintains the same formulation as Retinae but adapts its quantities to larger breeds, its recommended mode of use being 1 tablet per day for every 20kg (unlike Retinae which corresponds to 1 tablet per day for every 10kg).

Both Retinae and RetinaeXL provide nutrients to the retina, especially interesting in those breeds predisposed to retinopathies. Its main ingredients are Tagetes erecta (source of lutein and zeaxanthin) and omega 3 fatty acids that provide anti-inflammatory and antiangiogenic properties. These products also provide pets with Vitamins (C, E, B [B6, B9, B12]), Lactoferrin, Zinc and Copper.

Other product lines

In addition to our ophthalmological line, we will also be providing detailed information about our digestive and metabolic ranges, with the products Glyco, Flavum, Digestum and Colitum.

Iberzoo-Propet  serves as a platform to interact with professional colleagues and showcase our commitment to innovative veterinary care. Our team will be available to provide detailed information and answer any questions you may have about our products.

Stay tuned for updates and follow us on social media for more details as the event approaches. See you there!


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03/Apr/2023

The webinar, which will take place on April 27, will address the most used ingredients in veterinary ophthalmology and their role in certain diseases, as well as the scientific evidence that supports them.

A webinar on nutraceuticals in veterinary ophthalmology will take place on Thursday, April 27 at 9:00 p.m. organized by the European Society of Veterinary Ophthalmology (ESVO), which is supported by Dr+Vet.

This webinar will address the most commonly used ingredients in veterinary ophthalmology and their role in certain diseases, as well as the scientific evidence that supports them and the recommended protocols. The webinar, which will be broadcast in English, is free for all ESVO members and for non-ESVO members, the price will be 30 euros.

The webinar will be given by ophthalmology specialist Teresa Peña, who graduated in Veterinary Medicine from the Autonomous University of Barcelona (UAB) in 1987 and received a doctorate from the same university in 1993 with an experimental study on penetrating corneal grafts in dogs.

Teresa Peña completed her ophthalmology residency at the European College of Veterinary Ophthalmologists (ECVO) in a program at North Carolina State University. Since 1988 she has worked in the Department of Medicine and Surgery of the Faculty of Veterinary Medicine (UAB) and currently she is an associate professor of ophthalmology and surgery, and head of the Ophthalmology service at the Veterinary Teaching Clinical Hospital (FHCV-UAB).

She has been a diplomate of the ECVO since 1999, member of the Examinations Committee between 2002-2010 and member of the Credentials Committee since 2010 (chair of the committee since 2016). She served on the board of directors of the European Society of Veterinary Ophthalmology (treasurer from 1999 to 2006, vice-president from 2006 to 2007 and president from 2007 to 2009).

Likewise, the expert co-directs a postgraduate course in veterinary ophthalmology, to obtain an intermediate degree, as well as residency programs to be part of the ECVO. Her work and research are dedicated to ophthalmology, especially corneal pathology and surgery, and uveitis and ocular injuries caused by infectious diseases.

 


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09/Mar/2023

Dr+Vet launches a new formulation of LACRIMALIS with a higher concentration of fatty acids, EPA and DHA called LACRIMALIS+

As we have previously explained on the blog through the article “Key Points of Keratoconjunctivitis Sicca”, this is one of the most common ocular pathologies in the daily clinic of small animals. Let’s do a brief review and expansion of what was already discussed in the previous article:

What is keratoconjunctivitis sicca?

Keratoconjunctivitis Sicca (KCS) is an inflammatory disease of the ocular surface (cornea and conjunctiva) secondary to the deficiency of some of the phases of the tear film and which generates tear hyperosmolarity. This hyperosmolarity and increased friction will lead to secondary infections, dehydration and malnutrition of the cornea and conjunctiva and will increase the likelihood of corneal ulcerations.

What layers or phases make up the tear film?

– Mucinic layer: the innermost layer, it modifies the surface tension of the tear so that it adheres and distributes correctly on the surface of the cornea. Mucin is produced and secreted mainly in conjunctival goblet cells.

– Aqueous layer: the intermediate and by far the most abundant. It moisturizes the ocular surface and essential nutrients and oxygen for the metabolism of the cornea diffuse through it. It also has a physical effect by washing away corneal debris and foreign bodies. The aqueous portion is produced and secreted in the main and accessory lacrimal glands.

– Lipid layer: the outermost layer, it protects the aqueous layer from evaporation, allowing it to remain on the eye longer. In addition, it also increases the surface tension of the tear, preventing overflow (epiphora) along the eyelid edge and lubricates the eyelids. Produced and secreted mainly by the meibomian glands.

How are KCS classified?

The basic and most widespread classification is the following:

– Qualitative: due to pathological decrease in the lipid or mucoid components of the tear film, which makes it difficult for the tear to remain on the cornea, either due to excess evaporation or difficulty in adhering. It is usually due to damage or inflammation in the meibomian glands or goblet cells of the conjunctiva.

– Quantitative: due to pathological decrease in the aqueous component of the tear film. There may be different origins, the most common being localized and chronic immune-mediated inflammation of the lacrimal gland. It is the most common type of KCS, although most tend to progress to mixed KCS (quantitative and qualitative) over time.

How does LACRIMALIS+ intervene in the improvement of the clinical signs of KCS?

LACRIMALIS+ is a food supplement based on natural products that helps improve the clinical signs of dry eye by increasing the quantity and quality of tears.

Its formula rich in Omega 3 fatty acids helps modify the lipid profile of the tears, making them of better quality and thus reducing their evaporation. In addition, Omega 3 also provides an antioxidant and anti-inflammatory effect on the meibomian glands and the ocular surface.

LACRIMALIS+ is also enriched with Lactoferrin, a component naturally present in tears and which gives it anti-inflammatory, antimicrobial and antifungal properties.

Finally, its precise combination of minerals, such as zinc or copper, and vitamins C and E give it an antioxidant effect that enhances that of Omega 3 fatty acids.

What differentiates LACRIMALIS+ from the previous LACRIMALIS?

The main change in the formulation of LACRIMALIS concerns the source of Omega 3 fatty acids. In LACRIMALIS+ we have added purer sources of EPA and DHA. The liquid version is supplemented with a high proportion of fish oil, which contains EPA and DHA naturally and directly, also maintaining the contribution of alpha-linolenic acid already present in LACRIMALIS. As for the tablet version, EPA and DHA are provided pure to guarantee a much higher proportion.


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24/Oct/2022

Last week, from October 20th to 22nd, the National Congress of the Spanish Association of Veterinarians Specialists in Small Animals (AVEPA-SEVC) took place in Seville.

Dr+Vet was present with a stand presenting to the attendees its different lines of all-natural products to prevent and improve the symptoms of small animal pathologies, sold exclusively in the veterinary channel.

In addition to its ophthalmological line, already commercialized, two new nutraceutical lines were pre-launched: the Digestive line and the Metabolic line, which will be available for sale before the end of 2022.

There was a great acceptance of both the already known innovative ophthalmological line, as well as the two new lines, whose products continue to focus on innovation and provide effective solutions to improve compliance with treatments, offering complete, differentiating and exclusive products for veterinarians that adapt to their needs and those of their clients.

In this way, Dr+Vet remains true to its key values: innovation, effectiveness, convenience, exclusivity and affordability.

Many thanks to the many attendees who came to the Dr+Vet booth to learn more about the products!


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08/Jun/2022

Last June 2-5, the annual meeting of the European College of Veterinary Ophthalmologists (ECVO) was held at the Salzburg Congress Palace in Salzburg (Austria).

Even under the shadow of Covid-19, more than half of the 450 ophthalmologists registered for the congress decided to attend the different conferences in person, travelling from different European countries, such as the United Kingdom, Germany, Sweden, Finland, France, etc. or even from even more distant locations such as America or Asia.

Dr.Vet Pet Care successfully presented its unique and innovative ophthalmological line, indicated for patients with pathologies such as glaucoma, cataracts, retinopathies, dry eye / dry keratoconjunctivitis and palpebral pathologies. This range of nutraceutical products for veterinary ophthalmology has natural, effective and specific components to help alleviate, prevent or improve the symptoms of different ocular pathologies.

Both companies and veterinary specialists showed their interest in the different products as well as the possibility of acquiring them in their respective countries. In this way. Dr+Vet Pet Care was able to reaffirm its commitment to promote veterinary training, establish itself as a trusted brand among ophthalmologists and strengthen its relationship with veterinarians, in order to provide products that help improve the health of animals, their quality of life and highlight the importance of preventing certain ocular pathologies.


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28/Apr/2022

Today we will talk to you about one of the most common eye pathologies in dogs: dry eye disease or Keratoconjunctivitis Sicca.

Keratoconjunctivitis Sicca is an inflammatory disease of the ocular surface (cornea and conjunctiva) secondary to the deficiency of some of the phases of the tear film and which generates tear hyperosmolarity. This hyperosmolarity and increased friction will lead to secondary infections, dehydration and malnutrition of the cornea and conjunctiva and will increase the likelihood of corneal ulcerations. In turn, chronic inflammation of the ocular surface will also end up generating conjunctival hyperemia, hyperkeratinization and thickening of the corneal epithelium, corneal vascularization with increased migration of inflammatory cells and the deposition of pigment, lipids and calcium. The prognosis is usually favorable, although it will depend on the cause of the disease and whether effective treatment is implemented early and individualized for each patient.

There are two main classifications of Keratoconjunctivitis Sicca:

Qualitative: Pathological decrease in the lipid or mucoid components of the tear film. In this case, the lacrimal gland is functional and the hyperosmolarity of the tear is due to an increase in its evaporation. The cause of this type of Keratoconjunctivitis Sicca may be damage or acute/chronic inflammation in the meibomian glands and/or the goblet cells of the conjunctiva, such as in cases of infectious blepharitis, seborrheic dermatitis, etc.
Quantitative: Pathological decrease in the aqueous component of the tear film. In this case, hyperosmolarity is due to reduced secretion of the aqueous component under normal evaporation conditions. This is the most common initial presentation in dogs, although in most cases, a vicious circle is generated in which the other types of components of the tear film are also affected.

The causes of Quantitative Keratoconjunctivitis Sicca are varied, such as infectious diseases, endocrine diseases, systemic immune-mediated/autoimmune diseases, iatrogenic (surgical), etc. although the most common is localized and chronic immune-mediated inflammation of the lacrimal gland (immune-mediated adenitis). There are breeds of dogs and cats that are more predisposed, as we already mentioned in one of our previous posts on our social networks (Instagram and Linkedin), such as brachiocephalic breeds, West Highland White Terriers, Cocker Spaniels and American , etc.

The symptoms that may occur are: very characteristic mucous exudate, conjunctival hyperemia, opaque cornea, with neovascularization, corneal edema and ulceration, etc.

To reach a diagnosis, we will have to be attentive to the patient’s anamnesis and clinical history, perform a general and ophthalmoscopic examination, if we suspect systemic pathologies, general analytical and other complementary tests and followed by ophthalmological tests: Shirmer test, Fluorescein, Lysamine Green Test, TBUT (Tear Break-up Time), Impression Cytology and Osavet Test.

There are various types of systemic and topical medical treatments such as artificial tears (there is a wide variety), topical immunosuppressants, etc. and in most cases they can be applied together. Additionally, if there are secondary problems such as infections or corneal ulcers, these will also need to be treated. There are also surgical procedures such as parathyroid duct transposition, among others.

Another essential asset to help improve the symptoms of Keratoconjunctivitis Sicca, of which studies have already been carried out in dogs and which has others being carried out to demonstrate its effectiveness, will be supplementation with specific nutraceuticals such as Lacrimalis, rich in Omega-Fatty Acids. 3 that will improve the quality, stability and tear secretion, Lactoferrin with anti-inflammatory and antimicrobial properties on the ocular surface and antioxidants such as Vitamins E and C and the minerals Zinc and Copper.

From Dr+Vet Pet Care by Böthmen Pharma, we will present each of the different ophthalmological tests that we have mentioned little by little over the following weeks together with the Veterinary Ophthalmological Institute (IVO) so that you can learn more about them. lose!


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